Badania kliniczne

Skuteczność i bezpieczeństwo terapii Alpha-Stim® potwierdzono w ponad 100 badaniach, czyli w większej liczbie niż w przypadku większości leków. Warto mieć na uwadze, że badania dotyczące technologii Alpha-Stim® mają niezależne źródła finansowania. Źródła te obejmują amerykańskie Narodowe Instytuty Zdrowia (National Institutes of Health), Narodowy Instytut Raka (National Cancer Institute), Departament Obrony (Departament of Defense) i Departament ds. Weteranów (Departament of Veterans Affairs). 

Oprócz aktualnie trwających badań firma EPI przeprowadziła również ankiety wśród lekarzy i pacjentów stosujących terapię Alpha-Stim®. 47 lekarzy zgłosiło wyniki terapii przeprowadzonych u 500 pacjentów w 22 kategoriach diagnostycznych. Na podstawie tego badania ankietowego powstała 50-stronicowa analiza opublikowana w książce "The Science Behind Cranial Electrotherapy Stinulation dr. Daniela L. Kirscha.

Pod poniższym linkiem zamieszczona została rewizja literatury naukowej i klinicznej dotyczącej terapii MET i CES przy użyciu Alpha-Stim M. Przedstawiono tam dane kliniczne, skuteczność i korzyści płynące ze stosowania, a także ewentualne ryzyko. Raport został przygotowany w celu przedstawienia danych dotyczących Alpha -Stim M takich jak: status prawny, historia, mechanizmy, procesy leczenia i przegląd badań z podsumowaniami graficznymi i opatrzonymi komentarzami oraz zorganizowanych według metodologii badań i badanych zmiennych, takich jak RCT lub otwarte badanie lęku, bezsenności, depresji i/lub ból.

Zobacz ocenę kliniczną Alpha-Stim M

 

Bibliografia jest podzielona na następujące sekcje:

Stany lękowe

Bezsenność

Depresja

Ból

Badania mechanistyczne

Przegląd artykułów

  

STANY LĘKOWE

Podsumowanie graficzne – Pobierz PDF

Randomizowane badania kontrolowane

Hill, Nolan. The effects of alpha stimulation on induced anxiety. 2015. Digital Commons @ ACU, Electronic Theses and Dissertations. Paper 6. http://digitalcommons.acu.edu/etd/6. Zobacz artykuł

LU Ling, HU Jun. A comparative study of anxiety disorders treatment with Paroxetine in combination with cranial electrotherapy stimulation therapy. Medical Innovation of China, 11(08):080-082, 2014. Zobacz artykuł

Barclay TH, Barclay RD. A clinical trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders. 2014; 164:171-177. Presented at the American Psychological Association National Conference, Honolulu, HI, July 2013. Zobacz artykuł

Lee, S-H, Kim, W-Y, Lee C-H, Min, T-J, Lee Y-S, Kim J-H. Effects of cranial electrotherapy stimulation on preoperative anxiety, pain and endocrine response. Journal of International Medical Research. 2013; 41(6) 1788–179 Zobacz artykuł

Kolesos ON, Osionwo HO, Akkhigbe. The role of relaxation therapy and cranial electrotherapy stimulation in the management of dental anxiety in Nigeria. ISOR Journal of Dental and Medical Sciences. 2013; 10(4): 51-57Zobacz artykuł

Strentzsch, Julie A. An examination of cranial electrotherapy stimulation (CES) on alpha-amylase levels, cortisol levels and state-trait anxiety scores in the chronically mentally ill. Doctoral Dissertation. 2008. Saint Mary’s University, San Antonio, Texas.

Mellen, Ronald R. and Mackey, Wade. Cranial electrotherapy stimulation (CES) and the reduction of stress symptoms in a sheriff’s jail security and patrol officer population: a pilot study. American Jails. 2008; 22(5): 32-38Zobacz artykuł

Kim, Hyun Jung, Kim, Woon Young, Lee, Yoon Sook, Chang, Moon Seok, Kim, Jae Hwan, and Park, Young Cheol The effect of cranial electrotherapy stimulation on preoperative anxiety and hemodynamic responses. Korean Journal of Anesthesiology. 2008; 55(6): 657- 661Zobacz artykuł

Chen Yixin, Yu Lin, Zhang Jiuping, Li Lejia, Chen Tunong, Chen Yi. Results of cranial electrotherapy stimulation to children with mixed anxiety and depressive disorder. Shanghai Archives of Psychiatry. 2007; 19(4):203-205Zobacz artykuł

Winick, Reid L. Cranial electrotherapy stimulation (CES): a safe and effective low cost means of anxiety control in a dental practice. General Dentistry. 1999; 47(1):50-55. Zobacz artykuł

Voris, Marshall D. An investigation of the effectiveness of cranial electrotherapy stimulation in the treatment of anxiety disorders among outpatient psychiatric patients, impulse control parolees and pedophiles. Delos Mind/Body Institute Newsletter. 1995. Dallas and Corpus Cristi, Texas. Zobacz artykuł

Gibson, Thomas H. and O’Hair, Donald E. Cranial application of low level transcranial electrotherapy vs. relaxation instruction in anxious patients. American Journal of Electromedicine, 4(1):18-21, 1987. Doctoral dissertation (TG), California School of Professional Psychology. 1983. 152 stron. Zobacz artykuł

Otwarte badania kliniczne

Morriss R, Xydopoulos G, Craven M, Price L, Fordham R. Clinical effectiveness and cost minimisation model of Alpha-Stim cranial electrotherapy stimulation in treatment seeking patients with moderate to severe generalised anxiety disorderJournal of Affective Disorders. 2019, Czerwiec; 253:426-437. Zobacz artykuł

Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depressionJJ Psych Behav Sci. 2019; 6(1): 25-31. Zobacz artykuł

Kirsch TB, Kuhn J, Price LR, Marksberry J, Haltiwanger SG. A novel medical device that relieves anxiety, depression and pain while improving sleep in a population of teachersJournal of Depression and Anxiety. 2019; 8:334. Zobacz artykuł

Morrow DJ, Fischer EP, Walder AM, Jubran NI. Nonopioid Alternatives to Addressing Pain Intensity: A Retrospective Look at Two Noninvasive Pain Treatment DevicesFederal Practitioner. 2019, 36(4):181-187. Zobacz artykuł

Yennurajalingam S, Kang D-H, Hwu W-J, Padhye NS, Masino C, Dibaj SS, Liu DD, Williams JL, Lu Z, Bruera E. Cranial electrotherapy stimulation for the management of depression, anxiety, sleep disturbance, and pain in patients with advanced cancer: a preliminary study. Journal of Pain and Symptom Management.  2018, 55(2): 198–206. Zobacz artykuł

Mellen, Ronald R., Case, Jan and Ruiz, Deanna J. Cranial electrotherapy stimulation (CES) As a treatment for reducing stress and improving prefrontal cortex functioning in victims of domestic violence. International Association for Correctional and Forensic Psychology Newsletter. 48(3):12-15, 2016. Zobacz artykuł

Bystritsky, A., Kerwin, L., Feusner, J. A pilot study of cranial electrotherapy stimulation for generalized anxiety disorder. Journal of Clinical Psychiatry. 2008; 69:412-417. Zobacz artykuł

Lu XY, Wang AH, Li Y, Zhang JS, Liu BX. Safety and effectiveness of cranial electrotherapy stimulation in treating children with emotional disorders. Chinese Journal of Clinical Rehabilitation. 2005; 9(8):96-7. Zobacz artykuł

Overcash, Stephen J. Cranial electrotherapy stimulation in patients suffering from acute anxiety disorders. American Journal of Electromedicine. 1999; 16(1):49-51. Zobacz artykuł

Raporty

Hare, Jean P., Misialek, Leah H., Palis, Katy and Wong, Charmin. Using cranial electrotherapy stimulation therapy to treat behavioral health symptoms in a combat operational setting. Military Medicine. 2016; 181(11):1410-1412. Zobacz artykuł

Kirsch DL, Price LR, Nichols F, Marksberry JA and Platoni KT.  Efficacy of cranial electrotherapy stimulation for anxiety, PTSD, insomnia, and depression: US military Service Members and veterans self reports. The Army Medical Department Journal.  Październik-Grudzień 2014:46-54. Zobacz artykuł 

  

BEZSENNOŚĆ

Podsumowanie graficzne badań – Zobacz PDF

Randomizowane badania kontrolowane

Taylor, Ann Gill, Anderson, Joel G., Riedel, Shannon L., Lewis, Jante E., Kinser, Patricia A., and Bourguignon, Cheryl. Cranial electrical stimulation improves symptoms and functional status in individuals with fibromyalgia. Pain Management Nursing. 2013 Dec;14(4):327-335. Zobacz artykuł

Lichtbroun, Alan S., Raicer, Mei-Ming C., and Smith, Ray B. The treatment of fibromyalgia with cranial electrotherapy stimulation. Journal of Clinical Rheumatology. 2001; 7(2):72-78. Presented at the Fifteenth Annual International Symposium on Acupuncture and Electro-Therapeutics, Columbia University, New York, Październik 1999. Zobacz artykuł

Lande, R. Gregory and Gragnani, Cynthia. Efficacy of cranial electric stimulation for the treatment of insomnia: A randomized pilot study. Complementary Therapies in Medicine, 21(1):8-13, 2013. Zobacz artykuł

Otwarte badania kliniczne

Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depressionJJ Psych Behav Sci. 2019; 6(1): 25-31. Zobacz artykuł

Kirsch TB, Kuhn J, Price LR, Marksberry J, Haltiwanger SG. A novel medical device that relieves anxiety, depression and pain while improving sleep in a population of teachersJournal of Depression and Anxiety. 2019; 8:334. Zobacz artykuł

Yennurajalingam S, Kang D-H, Hwu W-J, Padhye NS, Masino C, Dibaj SS, Liu DD, Williams JL, Lu Z, Bruera E. Cranial electrotherapy stimulation for the management of depression, anxiety, sleep disturbance, and pain in patients with advanced cancer: a preliminary study. Journal of Pain and Symptom Management.  2018, 55(2): 198–206. Zobacz artykuł

Rickabaugh K, Johnson T, Martin S, Jones C and Onifer D. A retrospective review of patient perception of Alpha-Stimulation treatment. Poster presented at The Military Health System Symposium in Kissimmee, Florida. 2016; Sierpień 15-18. 

Raporty

Hare, Jean P., Misialek, Leah H., Palis, Katy and Wong, Charmin. Using cranial electrotherapy stimulation therapy to treat behavioral health symptoms in a combat operational setting. Military Medicine. 2016; 181(11):1410-1412. Zobacz artykuł

Clark, Nancy, Mills, Daniel & Marchant, Jeremy. Evaluation of the potential efficacy of the Alpha-Stim SCS in the horse. DeMontfort University Equestrian Centre and Field Station, Caythorpe, Lincolnshire, United Kingdom. Styczeń, 2000Zobacz artykuł 

 

DEPRESJA

Graficzne podsumowanie badań – Zobacz PDF

Randomizowane badania kontrolowane

Barclay TH, Barclay RD. A clinical trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders. 2014; 164:171-177. Presented at the American Psychological Association National Conference, Honolulu, HI, Lipiec 2013.Zobacz artykuł

Amr, Mostafa, El-Wasify, Mahmoud, Elmaadawi, Ahmed, Roberts, Jeannie, and El-Mallakn, Rif. Cranial electrotherapy stimulation for the treatment of chronically symptomatic bipolar patients. Journal of ECT.  2013; 29(2): 31-32. Zobacz artykuł

Mellen, Ronald R. and Mackey, Wade. Reducing sheriff’s officers’ symptoms of depression using cranial electrotherapy stimulation (CES): a control experimental study. The Correctional Psychologist. 2009; 41(1):9-15. Zobacz artykuł

Chen Yixin, Yu Lin, Zhang Jiuping, Li Lejia, Chen Tunong, Chen Yi. Results of cranial electrotherapy stimulation to children with mixed anxiety and depressive disorder. Shanghai Archives of Psychiatry. 2007; 19(4):203-205. Zobacz artykuł

Otwarte badania kliniczne

Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depressionJJ Psych Behav Sci. 2019; 6(1): 25-31. Zobacz artykuł

Kirsch TB, Kuhn J, Price LR, Marksberry J, Haltiwanger SG. A novel medical device that relieves anxiety, depression and pain while improving sleep in a population of teachersJournal of Depression and Anxiety. 2019; 8:334. Zobacz artykuł

Morrow DJ, Fischer EP, Walder AM, Jubran NI. Nonopioid Alternatives to Addressing Pain Intensity: A Retrospective Look at Two Noninvasive Pain Treatment DevicesFederal Practitioner. 2019, 36(4):181-187. Zobacz artykuł

Yennurajalingam S, Kang D-H, Hwu W-J, Padhye NS, Masino C, Dibaj SS, Liu DD, Williams JL, Lu Z, Bruera E. Cranial electrotherapy stimulation for the management of depression, anxiety, sleep disturbance, and pain in patients with advanced cancer: a preliminary study. Journal of Pain and Symptom Management.  2018, 55(2): 198–206. Zobacz artykuł

Rickabaugh K, Johnson T, Martin S, Jones C and Onifer D. A retrospective review of patient perception of Alpha-Stimulation treatment. Poster presented at The Military Health System Symposium in Kissimmee, Florida. 2016; Sierpień 15-18. Zobacz plakat

Bystritsky, A., Kerwin, L., Feusner, J. A pilot study of cranial electrotherapy stimulation for generalized anxiety disorder. Journal of Clinical Psychiatry. 2008; 69:412-417. Zobacz artykuł

Lu XY, Wang AH, Li Y, Zhang JS, Liu BX. Safety and effectiveness of cranial electrotherapy stimulation in treating children with emotional disorders. Chinese Journal of Clinical Rehabilitation. 2005; 9(8):96-7. Zobacz artykuł

Raporty

Hare, Jean P., Misialek, Leah H., Palis, Katy and Wong, Charmin. Using cranial electrotherapy stimulation therapy to treat behavioral health Symptoms in a combat operational setting. Military Medicine. 2016; 181(11):1410-1412. Zobacz artykuł

Kirsch DL, Price LR, Nichols F, Marksberry JA and Platoni KT.  Efficacy of cranial electrotherapy stimulation for anxiety, PTSD, insomnia, and depression: US military Service Members and veterans self reports. The Army Medical Department Journal.  October-December 2014:46-54. Zobacz artykuł 

  

BÓL

Graficzne podsumowanie badań– Zobacz PDF

Randomizowane badania kontrolowane

Taylor, Ann Gill, Anderson, Joel G., Riedel, Shannon L., Lewis, Jante E., Kinser, Patricia A., and Bourguignon, Cheryl. Cranial electrical stimulation improves symptoms and functional status in individuals with fibromyalgia. Pain Management Nursing. 2013 Grudzień;14(4):327-335. Zobacz artykuł

Taylor, Ann Gill, Anderson, Joel G., Riedel, Shannon L., Lewis, Janet E. and Bourguignon, Cheryl. A randomized, controlled, double-blind pilot study of the effects of cranial electrical stimulation on activity in brain pain processing regions in individuals with fibromyalgia. Explore. 2013; 9(1):32-40. Zobacz artykuł

Tan, Gabriel, Rintala, Diana, Jensen, Mark P., Richards, J. Scott, Holmes, Sally Ann, Parachuri, Rama, Lashgari-Saegh, Shamsi and Price, Larry R. Efficacy of cranial electrotherapy stimulation for neuropathic pain following spinal cord injury: a multi-site randomized controlled trial with a secondary 6-month open-label phase. The Journal of Spinal Cord Medicine. 2011; 34(3):285-296. Zobacz artykuł

Rintala, Diana H., Tan, Gabriel, Willson, Pamela , Bryant, Mon S., and Lai, Eugene C. H. Feasibility of using cranial electrotherapy stimulation for pain in persons with Parkinson’s disease. Parkinson’s Disease. 2010. 8 stron. Zobacz artykuł

Tan, Gabriel, Rintala, Diana H., Thornby, John, Yang, June, Wade, Walter, and Vasilev, Christine. Using cranial electrotherapy stimulation to treat pain associated with spinal cord Injury.Journal of Rehabilitation Research and Development. 2006; 43(4):461-474. Presented at the South Central VA Health Care Network’s Pain Management Initiative 2nd Annual Pain Management Symposium: Campaign Against Pain. Jackson, Mississippi, Kwiecień 7, 2006. Zobacz artykuł

Cork, Randall C., Wood, Patrick, Ming, Norbert, Shepherd, Clifton, Eddy, James, Price, Larry The effect of cranial electrotherapy stimulation (CES) on pain associated with fibromyalgia. The Internet Journal of Anesthesiology.  2004; 8(2). Zobacz artykuł

Tan, G., Rintala, D., Herrington, R., Yang, J., Wade, W., Vasilev, C. and Shanti, B.F. Treating spinal cord injury pain with cranial electrotherapy stimulation. Journal of Spinal Cord Medicine. 2003; 26(3). Poster presented at the Annual Meeting of the American Paraplegia Society, Las Vegas, Nevada, Wrzesień 2-4, 2003. Zobacz plakat

Lichtbroun, Alan S., Raicer, Mei-Ming C., and Smith, Ray B. The treatment of fibromyalgia with cranial electrotherapy stimulation. Journal of Clinical Rheumatology. 2001; 7(2):72-78. Presented at the Fifteenth Annual International Symposium on Acupuncture and Electro-Therapeutics, Columbia University, New York, Październik 1999. Zobacz artykuł

Sizer P, Sawyer S, Brismee J, Jones K, Bruce J, Slauterbeck J. The effect of microcurrent stimulation on postoperative pain after patellar tendon-bone anterior cruciate ligament reconstruction. Presented at the American Physical Therapy Association Annual Conference and Exposition, Indianapolis, Indiana; Czerwiec, 2000.

Heffernan, Michael. The effect of variable microcurrents on EEG spectrum and pain control. Canadian Journal of Clinical Medicine. 1997; 4(10):4-11. Zobacz artykuł

Zimmerman, Stephen I, & Lerner, Fred N. Biofeedback and electromedicine reduce the cycle of pain spasm pain in low back patients. Medical Electronics. June 1989; 117:108-120. Doctoral dissertation (SZ), City University Los Angeles, 284 stron, 1987. Zobacz artykuł

Roth, Peter M, & Thrash, William J. Effect of transcutaneous electrical nerve stimulation for controlling pain associated with orthodontic tooth movement. American Journal of Orthodontics. 1986; 90(2):132-138Zobacz artykuł

Otwarte badania kliniczne

Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depressionJJ Psych Behav Sci. 2019; 6(1): 25-31. Zobacz artykuł

Kirsch TB, Kuhn J, Price LR, Marksberry J, Haltiwanger SG. A novel medical device that relieves anxiety, depression and pain while improving sleep in a population of teachersJournal of Depression and Anxiety. 2019; 8:334. Zobacz artykuł

Morrow DJ, Fischer EP, Walder AM, Jubran NI. Nonopioid Alternatives to Addressing Pain Intensity: A Retrospective Look at Two Noninvasive Pain Treatment DevicesFederal Practitioner. 2019, 36(4):181-187. Zobacz artykuł

Yennurajalingam S, Kang D-H, Hwu W-J, Padhye NS, Masino C, Dibaj SS, Liu DD, Williams JL, Lu Z, Bruera E. Cranial electrotherapy stimulation for the management of depression, anxiety, sleep disturbance, and pain in patients with advanced cancer: a preliminary study. Journal of Pain and Symptom Management.  2018, 55(2): 198–206. Zobacz abstrakt

Tan, Gabriel, Dao, Tam K., Smith, Donna L., Robinson, Andrew and Jensen, Mark P. Incorporating complementary and alternative medicine (CAM) therapies to expand psychological services to veterans suffering from chronic pain. Psychological Services. 2010; 7(3):148–161. Zobacz artykuł

Holubec, Jerry T. Cumulative response from cranial electrotherapy stimulation (CES) for chronic pain Practical Pain Management. 2009; 9(9):80-83. Zobacz artykuł

Tae-Kyu Lee, Kwan-Sung Lee, Shin-Soo Jeun, Young-Kil Hong, Chun-Kun Park, Joon-Ki, Moon-Chan Kim. The control of chronic pain using microcurrent electrical therapy and cranial electrotherapy stimulation. From the Department of Neurosurgery, Kangnam St. Mary’s Hospital, College Of Medicine, and The Catholic University of Korea, Seoul, Korea. Presented at the Korea Society for Stereotactic & Functional Neurosurgery, Kwiecień 14, 2004.

Kulkarni, Arun D. and Smith, Ray B. The use of microcurrent electrical therapy and cranial electrotherapy stimulation in pain control. Clinical Practice of Alternative Medicine. 2001; 2(2):99-102Zobacz artykuł

Raporty

Keizer B, Sposato L, and Yancosek K. A progressive treatment for a chronic progressive disease: the war against complex regional pain syndrome. The Pain Practitioner. 2016; 6(1):26-31. Zobacz artykuł

Smith, Ray B. Is microcurrent stimulation effective in pain management? An additional Perspective. American Journal of Pain Management. 2001; 11(2):62-66. Zobacz artykuł

Alpher, Elliott J. and Kirsch, Daniel L. Traumatic brain injury and full body reflex sympathetic dystrophy patient treated with cranial electrotherapy stimulation. American Journal of Pain Management, 8(4):124-128, 1998. Zobacz artykuł

Bauer, William. Electrical treatment of severe head and neck cancer pain. Archives of Otolaryngology. 1983; 109(6):382-383Zobacz artykuł 

  

BADANIA MECHANISTYCZNE

Lande GR and Gragnani CT.  Prospective study of brain wave changes associated with cranial electrotherapy stimulationPrimary Care Companion for CNS Disorders. 2018; 20(1). VZobacz na PubMed | Zobacz abstrakt

Qiao Jainping, Weng Shenhong, Wang Pengwei, Long Jun, and Wang Zhishun. Normalization of intrinsic neural circuits governing Tourette’s Syndrome using cranial electrotherapy stimulation. Transactions on Biomedical Engineering. 2015 Maj;62(5): 1272-80. Zobacz artykuł

Feusner, J. D., Madsen, S., Moody, T. D., Bohon, C., Hembacher, E., Bookheimer, S. Y. and Bystritsky. Effects of cranial electrotherapy stimulation on resting state brain activity. Brain and Behavior. 2012. Pp 1-10Zobacz artykuł

Kennerly, Richard. Changes in quantitative EEG and low resolution tomography following cranial electrotherapy stimulation. Ph.D. Dissertation, the University of North Texas. 2006. 529 pp., 81 tabel, 233 danych liczbowych, 171 referencji. Zobacz artykuł

Kennerly, Richard. QEEG analysis of cranial electrotherapy: a pilot study. Journal of Neurotherapy. 2004; (8)2. Presented at the International Society for Neuronal Regulation annual conference, September 18-21, 2003 in Houston, Texas. Zobacz artykuł

Schroeder, M.J., and Barr, R.E. Quantitative analysis of electroencephalogram during cranial electrotherapy stimulation. Clinical Neurophysiology. 2001; 112:2075-2083. Doctoral dissertation, The Graduate School of the University of Texas at Austin, 191 stron, 1999. Zobacz artykuł

Heffernan, Michael. Comparative effects of microcurrent stimulation on EEG spectrum and correlation dimension. Integrative Physiological and Behavioral Science. 1996; 31(3):202-209. Zobacz artykuł

   

PRZEGLĄD ARTYKUŁÓW

Ryall, Jo-Ellyn. FDA moving toward CES neuromodulation approval for home use: are we ready? Missouri Psychiatry. First Quarter- 2017: 3. Zobacz artykuł

O’Hara, Christiane and Putnam, Helen (Netta). Sleep: the missing link. Sleep assessment and interventions for combat veterans with disrupted sleep. Combat Stress; 6(1): 3-18. Zobacz artykuł

Scarff, Jonathan R. When to consider cranial electrotherapy stimulation for patients with PTSD. Current Psychiatry. 2017; 16(2): 27-28. Zobacz artykuł

Massoumi L. Benefits of Alpha-Stim. The Carlat Report: Psychiatry. 2016; 14(11 &12): 1,4-5.

Moehringer J and Knabe MB. Transdermal electrical neurostimulation therapies in psychiatry: A review of the evidence. Psychiatric Annals, 46(10):589-593. Posted Październik 11, 2016.

Libretto S, Hilton L, Gordon S, and Zhang W. Effects of integrative PTSD treatment in a military health setting. Energy Psychology. 2015; 7(2):33-44. Zobacz artykuł

Anderson, Joel G., Kebaish, Samy A., Lewis, Janet E., and Taylor, Ann G. Effects of cranial electrical stimulation on activity in regions of the basal ganglia in individuals with fibromyalgia. The Journal of Alternative and Complementary Medicine. 2014; 20(3): 206-207. Zobacz artykuł

Horowitz, Sala. Transcranial magnetic stimulation and cranial electrotherapy stimulation. Alternative and Complementary Therapies.  2013; 19(4):188-193. Zobacz artykuł

Kirsch, Daniel L. and Nichols, Francine. Cranial electrotherapy stimulation for treatment of anxiety, depression and insomnia. Psychiatric Clinics of North America. 2013; 36(1):169-176. http://www.psych.theclinics.com. Zobacz artykuł

Farina Woodbury, Michael A. Efecto de la microcorriente sobre síntomas, de ansiedad, depresión, insomnio y dolor. Galenus. 2008; 1(5):15-18. Zobacz artykuł

Kirsch, Daniel L. and Gilula, Marshall. CES in the treatment of insomnia: a review and meta-analysis Practical Pain Management. 2007; 7(7):28-39. Zobacz artykuł

Tan Gabriel and Jensen Mark P. Integrating complementary and alternative medicine (CAM) into multidisciplinary chronic pain treatment. In Multidisciplinary Chronic Pain Management: a Guidebook for Program Development and Excellence of Treatment. Schatman and Campbell (editors). Taylor & Francis. 2007. Pp. 75-99. Zobacz artykuł

Kirsch, Daniel L. and Gilula, Marshall. Cranial electrotherapy stimulation in the treatment of depression – part 1. Practical Pain Management. 2007; 7(4):33-41. Zobacz artykuł

Kirsch, Daniel L. and Gilula, Marshall.Cranial electrotherapy stimulation in the treatment of depression – part 2. Practical Pain Management. 2007; 7(5):32-40. Zobacz artykuł

Kirsch, Daniel L. and Gilula, Marshall. A review and meta-analysis of cranial electrotherapy Stimulation in the treatment of anxiety disorders – part 1. Practical Pain Management. 2007; 7(2):40-47. Zobacz artykuł

Kirsch, Daniel L. and Gilula, Marshall. Cranial electrotherapy stimulation in the treatment of anxiety disorders: statistical considerations – part 2. Practical Pain Management. 2007; 7(3):22-39. Zobacz artykuł

Kirsch, Daniel L. Cranial electrotherapy stimulation for the treatment of anxiety, depression, insomnia and other conditions. Insert: Giordano, James. Illustrating how CES works. Natural Medicine. 2006; 23:118-120. Zobacz artykuł

Gilula, Marshall and Kirsch, Daniel L. Cranial Electrotherapy Stimulation Review: A Safer Alternative to Psychopharmaceuticals in the Treatment of Depression. Journal of Neurotherapy. 2005; 9(2): 7-26. Zobacz artykuł

Gilula, Marshall F. and Barach, Paul R. Cranial electrotherapy stimulation: a safe neuromedical treatment for anxiety, depression or insomnia. Southern Medical Journal. 2004; 97(12):1269-1270Zobacz artykuł

Kirsch, Daniel L. and Smith, Ray B. The use of cranial electrotherapy stimulation in the management of chronic pain: a review. NeuroRehabilitation. 2000; 14(2):85-94. Zobacz artykuł

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